Cassia Semen, derived from the dried ripe seeds of leguminous plant Cassia obtusifolia Linn.or Cassia.tora Linn., exhibits a variety of pharmacological BEARD OIL effects such as clearing heat to brighten the eyes, lubricating the intestine to relieve constipation, lowering blood pressure and lipids, hepatoprotection and anti-diabetes, etc.And due t

Abstract Regulatory Toning conditioner T cells play a crucial role in orchestrating immune response and maintaining immune tolerance, and the expression of the Foxp3 gene is indispensable to the differentiation of regulatory T cells.IL-4 shows strong inhibitory effects on Foxp3 expression and regulatory T cells differentiation, but the detailed mec

Puerarin (Pue) is the most abundant isoflavonoid in kudzu root.It has been widely used as a therapeutic agent for the treatment of cardiovascular diseases.However, poor-bioavailability of puerarin is the main obstacle to its widespread clinical applications.In this paper, HA-ADH-PS nanomicelles were prepared by chemical modification, noncovalent mo

Infections caused by human immunodeficiency virus Face Exfoliant (HIV) are considered one of the main public health problems worldwide.Antiretroviral therapy (ART) is the current modality of treatment for HIV-1 infection.It comprises the combined use of several drugs and can decrease the viral load and increase the CD4+ T cell count in patients wit

We consider an SIR endemic model in which the AUTOMATICS contact transmission function is related to the number of infected population.By theoretical analysis, it is shown that the model exhibits the bistability and undergoes saddle-node bifurcation, the Hopf bifurcation, and the Bogdanov-Takens bifurcation.Furthermore, we find that the threshold v